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BIO 240 General Genetics
Credit Hours:  3
Effective Term: Fall 2013
AGEC: None
Credit Breakdown: 3 Lectures
Times for Credit: 1
Grading Option: A/F

Description: Intensive introduction to the field of genetics including historical perspective, Mendelian insights and patterns of inheritance, exceptions to expected Mendelian ratios, quantitative genetics, non-Mendelian inheritance, pedigree analysis, molecular levels of gene expression and genetic control of metabolic pathways. This course also includes analytic dissection of molecular mechanisms behind DNA replication, transcription, translation, and gene regulation in both prokaryotes and eukaryotes, population genetics, genetics of behavior, and genetics of evolution and speciation.

Prerequisites: BIO181

Corequisites: None

Recommendations: Successful completion of BIO181 with a grade of "C" or better.

Measurable Student Learning Outcomes
1. (Comprehension Level) Identify and describe the cell cycle, including subphases of interphase and checkpoints.
2. (Application Level) Relate and explain the structure and function of the DNA molecule to its functional role in encoding genetic material.
3. (Application Level) Apply the principles of inheritance as formulated by Mendel by using Punnett Squares and/or pedigree analysis.
4. (Analysis Level) Apply the principles of extensions to Mendelian inheritance, including multiple allelism, lethal alleles, gene interactions, and sex-linked transmission by using Punnett Squares and/or pedigree analysis.
5. (Analysis Level) Analyze genetic data using statistical procedures.
6. (Comprehension Level) Identify and classify mutations in DNA and their effects on the resulting RNA and protein.
7. (Evaluation Level) Explain and make deductions about gene regulation with emphasis on the lac operon model.
8. (Comprehension Level) Explain the relationship between genetic, physical and cytogenetic maps.
9. (Analysis Level) Illustrate how information generated by genome sequencing projects can be used to discover practical knowledge about gene expression and relationships between species.
10. (Application Level) Apply the Hardy-Weinberg Law in analyzing population genetics for gene frequency, sex linkage, equilibrium and heterozygote frequency.
11. (Analysis Level) Analyze the difference between structural, functional and comparative genomics and how they differ from proteomics.
12. (Comprehension Level) Explain cancer genetics and give examples of oncogenes and tumor suppressor genes.
13. (Synthesis Level) Solve problems in population genetics using allelic and genotypic frequencies and use the Hardy-Weinberg Law to demonstrate the evolution of populations.
14. (Comprehension Level) Explain methods of reconstructing evolutionary history based upon cladistics, molecular clocks and general phylogenetics.
Internal/External Standards Accreditation
This course was developed according to the regional standards of the BIO240 course delivered at Mesa Community College. The core competencies for this course at MCC can be found here: http://www.maricopa.edu/curriculum/A-C/052bio240.html

The objectives for this course were also developed referencing the National Coalition for Health Professional Education in Genetics' "Core Competencies for All Health Professionals" found here: http://www.nchpeg.org/index.php?option=com_content&view=article&id=237&Itemid=84