powered by
Center for Curriculum and Transfer Articulation
Respiratory Care Pharmacology I
Course: RES134

First Term: 2009 Fall
 Lecture   2 Credit(s)   2 Period(s)   2 Load  
Subject Type: Occupational
Load Formula: C


Description: Pharmacologic principles related to the treatment of Acute and Chronic Pulmonary Disease. Information on bronchodilators, mucokinetics, surfactants, anti-inflammatory, antiasthmatic and anti-infective agents to include mechanism of action, general drug information, side effects, and respiratory care considerations.



MCCCD Official Course Competencies
1. Review basic pharmacologic principles. (I)
2. Review the basic physiology of smooth muscle relaxation, bronchial hygiene and inflammation in the airways. (II)
3. Differentiate the classes of bronchodilator medications according to their mechanism of action and clinical usage. (III)
4. Identify the appropriate pharmacological agents used to impact the physiology of mucus in the respiratory tract. (III)
5. Differentiate the anti-inflammatory and antiasthmatic classes of medications according to their mechanism of action and clinical usage. (III)
6. Given a patient with respiratory infection, identify appropriate antimicrobial therapy. (IV)
MCCCD Official Course Competencies must be coordinated with the content outline so that each major point in the outline serves one or more competencies. MCCCD faculty retains authority in determining the pedagogical approach, methodology, content sequencing, and assessment metrics for student work. Please see individual course syllabi for additional information, including specific course requirements.
 
MCCCD Official Course Outline
I. Pharmacologic Principles
   A. Competitive Antagonism
   B. Noncompetitive Antagonism
   C. Absorption and Degradation
II. Airway Physiology
   A. Review of Autonomic Nervous System
      1. Sympathetic
      2. Parasympathetic
   B. Adrenergic Receptors and Amines
      1. Chemistry
      2. Alpha and beta activity
      3. Receptor selectivity
   C. Muscarinic Antagonists
      1. Action
      2. Rationale
      3. Diagnostic use
   D. Airway Mediators
      1. Histamine
         a. Synthesis, release, and metabolism
         b. Action
         c. Release during allergic response
         d. Diagnostic use
         e. Agents used for protection against histamine induced reversible airway disease
      2. Prostaglandins
         a. Chemistry, synthesis, and inactivation
         b. Effects in the lungs
         c. Factors governing release in the lung
         d. Prostaglandins as therapeutic agents
   E. Mucociliary System
      1. Anatomy and Physiolgy
      2. Structure and Composition of Mucus
III. Drugs Used in the Treatment of Pulmonary Disease
   A. Bronchodilators
      1. Sympathomimetics
      2. Parasympatholytic
      3. Xanthines
   B. Mucokinetics and Surfactants
      1. Bland aerosols
      2. Mucolytics
      3. Surface-active agents
   C. Anti-Inflammatory and Antiasthmatic Agents
      1. Corticosteroids
      2. Antiasthmatics
      3. Prostaglandins
      4. Leukotrienes
      5. Treatment of Upper Airway Congestion
IV. Antimicrobial Agents
   A. Principles
      1. Antimicrobial therapy
      2. Identification of pathogens
      3. Modes of action
      4. Microbial resistance
      5. Superinfections
      6. Routes of administration
   B. Treatment of Pulmonary Infections
      1. Penicillins
      2. Cephalosporins
      3. Aminoglcosides
      4. Tetracyclines
      5. Sulfonamides
      6. Chloramphenicol
      7. Polymyxin B
      8. Erythromycin
      9. Clindamycin
      10. Antifungal
      11. Antituberculosis
   B. Diuretics
      1. action
      2. effects
      3. therapeutic uses
      4. types
   C. Agents affecting the central nervous system
      1. central nervous system
      2. narcotics and non narcotics
      3. narcotics antagonists
      4. sedative/hypnotics
      5. antipsychotic tranquilizers
   D. Respiratory stimulants
   E. Agents affecting the Cardiovascular system
      1. inotrophic
      2. antiarrythmic
      3. antianginal
      4. calcium- channel blockers
      5. beta blockers
      6. alpha agonists
      7. angiotensin converting enzymes
      8. drugs affecting the blood
         a. anticoagulants
         b. thrombolytics
         c. others
   F. Insulin
         c. others
 
MCCCD Governing Board Approval Date:  5/26/2009

All information published is subject to change without notice. Every effort has been made to ensure the accuracy of information presented, but based on the dynamic nature of the curricular process, course and program information is subject to change in order to reflect the most current information available.